USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: PSMD7_HUMAN USC-OGP 2-DE database:  PSMD7_HUMAN PSMD7_HUMAN General information about the entry View entry in simple text format Entry name PSMD7_HUMAN Primary accession number P51665 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=26S proteasome non-ATPase regulatory subunit 7; AltName: Full=26S proteasome regulatory subunit RPN8; AltName: Full=26S proteasome regulatory subunit S12; AltName: Full=Mov34 protein homolog; AltName: Full=Proteasome subunit p40;. Gene name Name=PSMD7 Synonyms=MOV34L Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1211: pI=6.91; Mw=37716 Cross-references UniProtKB/Swiss-Prot P51665; PSMD7_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PSMD7_HUMAN Primary accession number P51665 Secondary accession number(s) D3DWS9 Q6PKI2 Q96E97 Sequence was last modified on  May 10, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 163) Name and origin of the protein Description RecName: Full=26S proteasome non-ATPase regulatory subunit 7; AltName: Full=26S proteasome regulatory subunit RPN8; AltName: Full=26S proteasome regulatory subunit S12; AltName: Full=Mov34 protein homolog; AltName: Full=Proteasome subunit p40; Gene name Name=PSMD7 Synonyms=MOV34L Encoded on Name=PSMD7; Synonyms=MOV34L Keywords 3D-structure; Acetylation; Complete proteome; Isopeptide bond; Proteasome; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D50063; BAA08780.1; -; mRNA EMBL CH471166; EAW59162.1; -; Genomic_DNA EMBL CH471166; EAW59163.1; -; Genomic_DNA EMBL BC000338; AAH00338.1; ALT_SEQ; mRNA EMBL BC012606; AAH12606.1; -; mRNA CCDS CCDS10910.1; -; . PIR JC4154; JC4154; . PIR S65491; S65491; . RefSeq NP_002802.2; NM_002811.4; . UniGene Hs.440604; -; . PDB 2O95; X-ray; 1.95 A; A/B=1-186 PDB 2O96; X-ray; 3.00 A; A/B=1-177 PDB 5GJQ; EM; 4.50 A; U=1-324 PDB 5GJR; EM; 3.50 A; 8/U=1-324 PDB 5L4K; EM; 4.50 A; U=1-324 PDB 5T0C; EM; 3.80 A; AZ/BZ=1-324 PDB 5T0G; EM; 4.40 A; Z=1-324 PDB 5T0H; EM; 6.80 A; Z=1-324 PDB 5T0I; EM; 8.00 A; Z=1-324 PDB 5T0J; EM; 8.00 A; Z=1-324 PDBsum 2O95; -; . PDBsum 2O96; -; . PDBsum 5GJQ; -; . PDBsum 5GJR; -; . PDBsum 5L4K; -; . PDBsum 5T0C; -; . PDBsum 5T0G; -; . PDBsum 5T0H; -; . PDBsum 5T0I; -; . PDBsum 5T0J; -; . ProteinModelPortal P51665; -; . SMR P51665; -; . BioGrid 111685; 111; . DIP DIP-27572N; -; . IntAct P51665; 48; . MINT MINT-5002613; -; . STRING 9606.ENSP00000219313; -; . MEROPS M67.973; -; . iPTMnet P51665; -; . PhosphoSitePlus P51665; -; . BioMuta PSMD7; -; . DMDM 20532412; -; . EPD P51665; -; . MaxQB P51665; -; . PaxDb P51665; -; . PeptideAtlas P51665; -; . PRIDE P51665; -; . DNASU 5713; -; . Ensembl ENST00000219313; ENSP00000219313; ENSG00000103035; . GeneID 5713; -; . KEGG hsa:5713; -; . UCSC uc002fcq.3; human; . CTD 5713; -; . DisGeNET 5713; -; . GeneCards PSMD7; -; . HGNC HGNC:9565; PSMD7; . HPA CAB019379; -; . HPA HPA049824; -; . HPA HPA056069; -; . MIM 157970; gene; . neXtProt NX_P51665; -; . OpenTargets ENSG00000103035; -; . PharmGKB PA33911; -; . eggNOG KOG1556; Eukaryota; . eggNOG COG1310; LUCA; . GeneTree ENSGT00530000063075; -; . HOGENOM HOG000209236; -; . HOVERGEN HBG035951; -; . InParanoid P51665; -; . KO K03038; -; . OMA MPVNHQI; -; . OrthoDB EOG091G0DX6; -; . PhylomeDB P51665; -; . Reactome R-HSA-1169091; Activation of NF-kappaB in B cells; . Reactome R-HSA-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; . Reactome R-HSA-1236974; ER-Phagosome pathway; . Reactome R-HSA-1236978; Cross-presentation of soluble exogenous antigens (endosomes); . Reactome R-HSA-174084; Autodegradation of Cdh1 by Cdh1:APC/C; . Reactome R-HSA-174113; SCF-beta-TrCP mediated degradation of Emi1; . Reactome R-HSA-174154; APC/C:Cdc20 mediated degradation of Securin; . Reactome R-HSA-174178; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-180534; Vpu mediated degradation of CD4; . Reactome R-HSA-180585; Vif-mediated degradation of APOBEC3G; . Reactome R-HSA-187577; SCF(Skp2)-mediated degradation of p27/p21; . Reactome R-HSA-195253; Degradation of beta-catenin by the destruction complex; . Reactome R-HSA-202424; Downstream TCR signaling; . Reactome R-HSA-211733; Regulation of activated PAK-2p34 by proteasome mediated degradation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2871837; FCERI mediated NF-kB activation; . Reactome R-HSA-349425; Autodegradation of the E3 ubiquitin ligase COP1; . Reactome R-HSA-350562; Regulation of ornithine decarboxylase (ODC); . Reactome R-HSA-382556; ABC-family proteins mediated transport; . Reactome R-HSA-450408; AUF1 (hnRNP D0) binds and destabilizes mRNA; . Reactome R-HSA-4608870; Asymmetric localization of PCP proteins; . Reactome R-HSA-4641257; Degradation of AXIN; . Reactome R-HSA-4641258; Degradation of DVL; . Reactome R-HSA-5358346; Hedgehog ligand biogenesis; . Reactome R-HSA-5362768; Hh mutants that don't undergo autocatalytic processing are degraded by ERAD; . Reactome R-HSA-5607761; Dectin-1 mediated noncanonical NF-kB signaling; . Reactome R-HSA-5607764; CLEC7A (Dectin-1) signaling; . Reactome R-HSA-5610780; Degradation of GLI1 by the proteasome; . Reactome R-HSA-5610783; Degradation of GLI2 by the proteasome; . Reactome R-HSA-5610785; GLI3 is processed to GLI3R by the proteasome; . Reactome R-HSA-5632684; Hedgehog 'on' state; . Reactome R-HSA-5658442; Regulation of RAS by GAPs; . Reactome R-HSA-5668541; TNFR2 non-canonical NF-kB pathway; . Reactome R-HSA-5676590; NIK-->noncanonical NF-kB signaling; . Reactome R-HSA-5678895; Defective CFTR causes cystic fibrosis; . Reactome R-HSA-5687128; MAPK6/MAPK4 signaling; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-68827; CDT1 association with the CDC6:ORC:origin complex; . Reactome R-HSA-68949; Orc1 removal from chromatin; . Reactome R-HSA-69017; CDK-mediated phosphorylation and removal of Cdc6; . Reactome R-HSA-69229; Ubiquitin-dependent degradation of Cyclin D1; . Reactome R-HSA-69481; G2/M Checkpoints; . Reactome R-HSA-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . ChiTaRS PSMD7; human; . EvolutionaryTrace P51665; -; . GeneWiki PSMD7; -; . GenomeRNAi 5713; -; . PRO PR:P51665; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000103035; -; . CleanEx HS_PSMD7; -; . ExpressionAtlas P51665; baseline and differential; . Genevisible P51665; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0000502; C:proteasome complex; IDA:UniProtKB; . GO GO:0005838; C:proteasome regulatory particle; TAS:ProtInc; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent; TAS:Reactome GO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0038061; P:NIK/NF-kappaB signaling; TAS:Reactome; . GO GO:0090263; P:positive regulation of canonical Wnt signaling pathway; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0000209; P:protein polyubiquitination; TAS:Reactome; . GO GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome; . GO GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; TAS:Reactome; . GO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome; . GO GO:0055085; P:transmembrane transport; TAS:Reactome; . GO GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:Reactome; . GO GO:0060071; P:Wnt signaling pathway; planar cell polarity pathway; TAS:Reactome CDD cd08062; MPN_RPN7_8; 1; . InterPro IPR000555; JAMM/MPN+_dom; . InterPro IPR033858; MPN_RPN7_8; . InterPro IPR024969; Rpn11/EIF3F_C; . PANTHER PTHR10540:SF13; PTHR10540:SF13; 1; . Pfam PF01398; JAB; 1; . Pfam PF13012; MitMem_reg; 1; . SMART SM00232; JAB_MPN; 1; .

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